"Gut Fauna" sounds like the name of some kind of dance-punk band.
In my research for this comic, I have learned that biomes are generally fairly big. A macrobiome would therefore be very large, like an entire planet. Thus, a wolf would be far too small to be considered pill sized in reference to a macrobiome. What the patient would actually need to swallow would be more like a largish island, like, say, Kangaroo Island.
Aside from that, I really don't have any problems with this comic. I don't think it's that funny but all the pieces are in the right places. The alt-text should definitely have been the fourth panel, though, it'd have added a lot.
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