XKCD Isn't Funny - #1702 - Home itch Remedies
This comic should have just ended in the second panel. Cut out the fourth line of dialogue, too. The funniest (and truest) part of the comic is "I just want sympathy".
Maybe it's just because I live in the northeast where everyone just hates things all day, but are weird home remedies actually a widespread phenomenon? I can't think of a single example I've seen in my life, at least not for bug bites. Hiccups, sure, because it's always fun to get your friends to hurt themselves, but not bug bites.
I think Randy thinks that any exaggeration is inherently funny. It can't just be "rub a mixture of honey and syrup on it" it has to be this impossibly elaborate thing. Just like every good lie has a little bit of truth, every good joke still reflects reality. This exaggeration goes too far out of the bounds of normalcy and becomes meaninglessly absurd.